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I've not seen it specifically in rats, but the only time I've seen something similar is with severe calcium deficiency. Calcium is very important for making muscles work properly, and if blood calcium levels are drastically low, it can cause all sorts of weird things, like not being able to use the back legs, trembling/shaking, and even seizures. Aside from that, I'm not sure what else to suggest - my first instinct would have been some kind of physical injury, but if you rule that out, I'm not sure what else to suggest. Hopefully someone with more direct knowledge of rat illnesses has something more for you.
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