i know exactly how you feel! i made the mistake of putting my rabbit's cage up high and level with my bed so she would feel safe but would also be able to jump out of her cage onto my bed to get down to the floor. however! she decided that my bed was where the bathroom was and she has peed on my bed SO many times as well as everything else! finally - after washing my comforter 7 days a week- i had to buy a vinyl tablecloth and put it over my bed during the day and also put a big litter box against the wall. she now uses the litter box but it still sucks because i have to keep it on my bed at all times beacuse my older rabbit refuses to be caged at all now.
eventually i think i'm going to have to buy a bunk bed and sleep on the top level just to escape the situation. LOL