I think that would be fine for 2 days. I know you normally have them out a lot, and it won't scar them for life or anything. Just relax and have a good time with your bf's family.
When my dad's whole family was visiting I had a hard time spending time with my guys too. If it was quiet and not too hectic I would try to take just one out and put him in my sweater to hang out while I socialized. It's easier to keep track of one, and with all the unfamiliar smells and noises they were content to stay with me and didn't try to wander off and explore. It got them out of the cage more than the small amount of time I had to dedicate to just them.
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Six new rats