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For Use on Indoor and Outdoor Cats

Find the right treatment for your cat
Advantage II for cats is for use on both indoor and outdoor cats and kittens 8 weeks of age or older, weighing at least 2 pounds.
Select the right size for your cat based on weight.

  • Kitten: 2-5 pounds
  • Small cats: 5-9 pounds
  • Large cats: Over 9 pounds

How to Apply

How to apply
Be sure to use the entire tube of Advantage II when applying it to your cat. Part the hair on your cat’s neck at the base of skull until the skin is visible. Squeeze the tube to expel the entire contents directly on the skin. Do not get the product in your cat’s eyes or allow your cat to ingest the product. Do not allow the product to run off. Do not split tubes between multiple cats. See package insert for additional details.

How Does it Work?

How does it work?
Advantage II for cats is a topical flea treatment that spreads over the skin and hair. Advantage II kills through contact, so fleas don’t have to bite your cat to die. With oral flea treatments, fleas must bite your cat and ingest the medication before they are killed.

cat flea lifecycle

Frequently Asked Questions
Advantage II

How long does it take to work on fleas?
Advantage II for cats kills fleas within 12 hours of application.
Advantage II

Why do I still see fleas after using Advantage II?
The fleas you see on your pet today are not the same fleas that you initially saw when you applied the treatment. These are new fleas from the environment that have since developed into adults and jumped on your cat. As the weeks go by, these developing stages should run their course and disappear. Be sure to treat your pet’s environment, including your home, yard, carpet, bedding, etc.
Advantage II

Does it expire?
There is no expiration date required on the packaging by the EPA for Advantage II for cats. The product should be kept in its original packaging and stored as directed on the label.
Advantage II

What are the key ingredients?
Advantage II for cats contains two active ingredients: imidacloprid, which attacks the flea’s nervous system, to paralyze and kill it, and pyriproxyfen, which prevents eggs and larvae from maturing.

Advantage II topical flea treatment and prevention for large cats over 9 lbs is a veterinarian-recommended, monthly application that kills fleas through contact, so they don't have to bite your cat to die. The protection of Advantage II kills fleas in multiple life stages, including eggs, larvae and adults, effectively breaking the flea life cycle to control existing flea infestations on your cat and prevent further infestations. This 6-dose cat flea treatment comes in a convenient topical liquid that is easy to apply and fragrance free. A single application of Advantage II cat flea treatment for large cats starts working in 12 hours and keeps killing fleas for up to 30 days. Even indoor cats need flea protection because humans and other pets can bring fleas into your home. Advantage II is also available in a formula for dogs. Fight the misery of biting fleas with the help of Advantage II 6-month flea prevention and treatment for large cats.
Features & details
  • 6-month supply of advantage II topical large cat flea prevention
  • Easy-to-apply and pre-measured flea treatment application tubes, fragrance-free and waterproof after 24 hours
  • Advantage II large cat flea prevention kills fleas through contact, meaning fleas don’t have to bite your cat in order to die.Avoid contact with eyes or clothing
  • Starts working within 12 hours and protects your cat for up to 30 days. Kills fleas in multiple life stages; Eggs, larvae and adults to break the flea life cycle
  • Vet recommended, fragrance free and designed specifically to treat and prevent fleas on cats
Product information 6-pack , Large Cat Only

Item Weight‎0.8 ounces
Item model number‎81520232
Customer Reviews4.6 out of 5 stars
Date First Available‎March 2, 2011
Item Package Dimensions L x W x H‎6.65 x 4.33 x 1.42 inches
Item Dimensions LxWxH‎6.5 x 1 x 4.25 inches
Item Weight‎0.8 Ounces
Brand Name‎Advantage
Target Audience Keyword‎House-cats
Directions‎Application Instructions: 1. Use only on cats. 2. Hold applicator tube in an upright position. Pull cap off tube. 3. Turn the cap around and place other end of cap back on tube. Twist cap to break seal, then remove cap from tube. 4. Part the hair at the base of the cat’s skull until skin is visible. 5. Evenly apply the entire contents of the Advantage II tube directly on the skin by squeezing the entirety of the contents in that one spot. Do not get this product in your cat’s eyes, or allow your cat to ingest this product.
Country of Origin‎United States
Model Name‎Flea Prevtion for Cats Over 9 lbs, 6 Pack, Advantage II
Age Range Description‎Adult
Care Instructions‎Topical
Number of Items‎1
Style‎Large Cat Only
Breed Recommendation‎Large cat, over 9 lbs
Included Components‎FLEA TOPICALS
Specific Uses for Product‎Coat

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